And it is the Welsh who look the best value to claim their first crown since 2013 in head coach Warren Gatland’s final campaign.
An opening encounter against France is a challenging start, but Wales have won six of their last seven clashes with Les Bleus including two of the last three in Paris, and for once they go into the tournament buoyed by an autumn clean sweep and with nine straight Test victories under their belts.
This has always been a tight fixture but even with injuries in the camp Wales look better equipped to get into their stride than a reshuffled French line-up.
Then it’s Italy away before home encounters with title rivals England and Ireland and Wales, who have a habit of growing into the tournament, should start getting some sidelined players back and fresh to go.
Scotland away completes the Wales fixture list and the Scots will no doubt have a say in the title’s destination, although matching last season’s three wins will not be easy.
They open up at home to Italy but must play France and England away knowing they have never won either fixture in the Six Nations era, and while they enjoy home comforts against Wales and Ireland, both teams suffered painful defeats at Murrayfield two years ago and are sure to go all-in.
Scotland could well struggle in both those matches and one victory may be all Gregor Townsend’s men have to celebrate at the end.
France are a similar price to Scotland in the outright betting but face three away matches and a record of two road wins in their last ten – both over Italy – doesn’t bode well.
Italy have not won a Six Nations match in the last three seasons and it’s just 1-4 that they suffer a similar winless fate.
There are plenty of exciting back-three players crowded at the head of the top try scorer market, but given England’s kind home schedule, Red Rose winger Jonny May looks the pick of the prices.
His pace and finishing prowess make him a regular first-choice starter and his eight tries in all competitions made him England’s top try scorer last year.